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Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines
BACKGROUND: Hedgehog (Hh) signaling is a conserved morphogenetic pathway which plays critical roles in embryonic development, with emerging evidence also supporting a role in healing and repair processes and tumorigenesis. The Gli family of transcription factors (Gli1, 2 and 3) mediate the Hedgehog...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542994/ https://www.ncbi.nlm.nih.gov/pubmed/18789160 http://dx.doi.org/10.1186/1471-2121-9-49 |