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Thalidomide-Related Eosinophilic Pneumonia: A case report and brief literature review

Thalidomide has regained value in the multimodality treatment of leprosy, multiple myeloma, prostate, ovarian and renal cancer. Complications related to arterial and venous complications are well described. However, pulmonary complications remain relatively uncommon. The most common pulmonary side-e...

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Autores principales: Tilluckdharry, Lisa, Dean, Robert, Farver, Carol, Ahmad, Muzaffar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546376/
https://www.ncbi.nlm.nih.gov/pubmed/18778468
http://dx.doi.org/10.1186/1757-1626-1-143
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author Tilluckdharry, Lisa
Dean, Robert
Farver, Carol
Ahmad, Muzaffar
author_facet Tilluckdharry, Lisa
Dean, Robert
Farver, Carol
Ahmad, Muzaffar
author_sort Tilluckdharry, Lisa
collection PubMed
description Thalidomide has regained value in the multimodality treatment of leprosy, multiple myeloma, prostate, ovarian and renal cancer. Complications related to arterial and venous complications are well described. However, pulmonary complications remain relatively uncommon. The most common pulmonary side-effect reported is non-specific dyspnea. We report a patient with multiple myeloma, who developed an eosinophilic pneumonia, shortly after starting thalidomide. She had complete resolution of her symptoms and pulmonary infiltrates on discontinuation of the drug and treatment with corticosteroids. Physicians should be cognizant of this potential complication in patients receiving thalidomide who present with dyspnea and pulmonary infiltrates.
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spelling pubmed-25463762008-09-20 Thalidomide-Related Eosinophilic Pneumonia: A case report and brief literature review Tilluckdharry, Lisa Dean, Robert Farver, Carol Ahmad, Muzaffar Cases J Case Report Thalidomide has regained value in the multimodality treatment of leprosy, multiple myeloma, prostate, ovarian and renal cancer. Complications related to arterial and venous complications are well described. However, pulmonary complications remain relatively uncommon. The most common pulmonary side-effect reported is non-specific dyspnea. We report a patient with multiple myeloma, who developed an eosinophilic pneumonia, shortly after starting thalidomide. She had complete resolution of her symptoms and pulmonary infiltrates on discontinuation of the drug and treatment with corticosteroids. Physicians should be cognizant of this potential complication in patients receiving thalidomide who present with dyspnea and pulmonary infiltrates. BioMed Central 2008-09-08 /pmc/articles/PMC2546376/ /pubmed/18778468 http://dx.doi.org/10.1186/1757-1626-1-143 Text en Copyright © 2008 Tilluckdharry et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tilluckdharry, Lisa
Dean, Robert
Farver, Carol
Ahmad, Muzaffar
Thalidomide-Related Eosinophilic Pneumonia: A case report and brief literature review
title Thalidomide-Related Eosinophilic Pneumonia: A case report and brief literature review
title_full Thalidomide-Related Eosinophilic Pneumonia: A case report and brief literature review
title_fullStr Thalidomide-Related Eosinophilic Pneumonia: A case report and brief literature review
title_full_unstemmed Thalidomide-Related Eosinophilic Pneumonia: A case report and brief literature review
title_short Thalidomide-Related Eosinophilic Pneumonia: A case report and brief literature review
title_sort thalidomide-related eosinophilic pneumonia: a case report and brief literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546376/
https://www.ncbi.nlm.nih.gov/pubmed/18778468
http://dx.doi.org/10.1186/1757-1626-1-143
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