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The transcriptional cofactor MIER1-beta negatively regulates histone acetyltransferase activity of the CREB-binding protein

BACKGROUND: Mier1 encodes a novel transcriptional regulator and was originally isolated as a fibroblast growth factor early response gene. Two major protein isoforms have been identified, MIER1α and β, which differ in their C-terminal sequence. Previously, we demonstrated that both isoforms recruit...

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Detalles Bibliográficos
Autores principales: Blackmore, Tina M, Mercer, Corinne F, Paterno, Gary D, Gillespie, Laura L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546418/
https://www.ncbi.nlm.nih.gov/pubmed/18721470
http://dx.doi.org/10.1186/1756-0500-1-68