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Spatiotemporal Regulation of ERK2 by Dual Specificity Phosphatases

Although many stimuli activate extracellular signal-regulated kinases 1 and 2 (ERK1/2), the kinetics and compartmentalization of ERK1/2 signals are stimulus-dependent and dictate physiological consequences. ERKs can be inactivated by dual specificity phosphatases (DUSPs), notably the MAPK phosphatas...

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Detalles Bibliográficos
Autores principales:	Caunt, Christopher J., Armstrong, Stephen P., Rivers, Caroline A., Norman, Michael R., McArdle, Craig A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Mechanisms of Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546534/ https://www.ncbi.nlm.nih.gov/pubmed/18650424 http://dx.doi.org/10.1074/jbc.M801500200

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