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Confidence interval approach for evaluating bias in laboratory methods
A statistically significant difference in mean values between two laboratory quantitation methods is interpreted as a bias. Sometimes such a difference is so minute that it does not constitute any practical concern. An alternative approach is to test statistically whether the two methods are close e...
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| Formato: | Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
1988
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547746/ https://www.ncbi.nlm.nih.gov/pubmed/18925202 http://dx.doi.org/10.1155/S1463924688000276 |
| _version_ | 1782159330032746496 |
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| author | Yee, K. F. |
| author_facet | Yee, K. F. |
| author_sort | Yee, K. F. |
| collection | PubMed |
| description | A statistically significant difference in mean values between two laboratory quantitation methods is interpreted as a bias. Sometimes such a difference is so minute that it does not constitute any practical concern. An alternative approach is to test statistically whether the two methods are close enough, not for equality. This is to look at the confidence interval of the mean method difference and does not entail any additional statistical tests. |
| format | Text |
| id | pubmed-2547746 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1988 |
| publisher | Hindawi Publishing Corporation |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-25477462008-10-16 Confidence interval approach for evaluating bias in laboratory methods Yee, K. F. J Automat Chem Research Article A statistically significant difference in mean values between two laboratory quantitation methods is interpreted as a bias. Sometimes such a difference is so minute that it does not constitute any practical concern. An alternative approach is to test statistically whether the two methods are close enough, not for equality. This is to look at the confidence interval of the mean method difference and does not entail any additional statistical tests. Hindawi Publishing Corporation 1988 /pmc/articles/PMC2547746/ /pubmed/18925202 http://dx.doi.org/10.1155/S1463924688000276 Text en Copyright © 1988 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Research Article Yee, K. F. Confidence interval approach for evaluating bias in laboratory methods |
| title | Confidence interval approach for evaluating bias in laboratory methods |
| title_full | Confidence interval approach for evaluating bias in laboratory methods |
| title_fullStr | Confidence interval approach for evaluating bias in laboratory methods |
| title_full_unstemmed | Confidence interval approach for evaluating bias in laboratory methods |
| title_short | Confidence interval approach for evaluating bias in laboratory methods |
| title_sort | confidence interval approach for evaluating bias in laboratory methods |
| topic | Research Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547746/ https://www.ncbi.nlm.nih.gov/pubmed/18925202 http://dx.doi.org/10.1155/S1463924688000276 |
| work_keys_str_mv | AT yeekf confidenceintervalapproachforevaluatingbiasinlaboratorymethods |