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Post-column coulometric generation and cyclic voltammetric identification of the free radical of the antineoplastic agent etoposide (VP 16-213)
It has been suggested that etoposide can be transformed ‘in vivo’ into a radical intermediate, which may be involved in the irreversible binding of etoposide to microsomal proteins and in DNA damage. To investigate some physico-chemical properties, the on-line coulometric production of this free rad...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
1988
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547747/ https://www.ncbi.nlm.nih.gov/pubmed/18925200 http://dx.doi.org/10.1155/S1463924688000252 |