Hepatocyte RXRalpha deficiency in matured and aged mice: impact on the expression of cancer-related hepatic genes in a gender-specific manner

BACKGROUND: The occurrence of liver cancer is higher in males than in females, and the incidence increases during aging. Signaling pathways regulated by retinoid × receptor α (RXRα) are involved in hepatocellular carcinogenesis. The phenotype of hepatocyte RXRα deficient mice is different between ge...

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Detalles Bibliográficos
Autores principales: Guo, Minglei, Gong, Lei, He, Lin, Lehman-McKeeman, Lois, Wan, Yu-Jui Yvonne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547858/
https://www.ncbi.nlm.nih.gov/pubmed/18755030
http://dx.doi.org/10.1186/1471-2164-9-403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547858/
https://www.ncbi.nlm.nih.gov/pubmed/18755030
http://dx.doi.org/10.1186/1471-2164-9-403

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