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Effects of experimental design on calibration curve precision in routine analysis

A computational program which compares the effciencies of different experimental designs with those of maximum precision (D-optimized designs) is described. The program produces confidence interval plots for a calibration curve and provides information about the number of standard solutions, concent...

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Detalles Bibliográficos
Autores principales: Pimentel, Maria Fernanda, Neto, Benício de Barros, Saldanha, Teresa Cristina B., Araújo, Mário César Ugulino
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2548143/
https://www.ncbi.nlm.nih.gov/pubmed/18924816
http://dx.doi.org/10.1155/S1463924698000029
Descripción
Sumario:A computational program which compares the effciencies of different experimental designs with those of maximum precision (D-optimized designs) is described. The program produces confidence interval plots for a calibration curve and provides information about the number of standard solutions, concentration levels and suitable concentration ranges to achieve an optimum calibration. Some examples of the application of this novel computational program are given, using both simulated and real data.