Effects of experimental design on calibration curve precision in routine analysis

A computational program which compares the effciencies of different experimental designs with those of maximum precision (D-optimized designs) is described. The program produces confidence interval plots for a calibration curve and provides information about the number of standard solutions, concent...

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Detalles Bibliográficos
Autores principales: Pimentel, Maria Fernanda, Neto, Benício de Barros, Saldanha, Teresa Cristina B., Araújo, Mário César Ugulino
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2548143/
https://www.ncbi.nlm.nih.gov/pubmed/18924816
http://dx.doi.org/10.1155/S1463924698000029
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author Pimentel, Maria Fernanda
Neto, Benício de Barros
Saldanha, Teresa Cristina B.
Araújo, Mário César Ugulino
author_facet Pimentel, Maria Fernanda
Neto, Benício de Barros
Saldanha, Teresa Cristina B.
Araújo, Mário César Ugulino
author_sort Pimentel, Maria Fernanda
collection PubMed
description A computational program which compares the effciencies of different experimental designs with those of maximum precision (D-optimized designs) is described. The program produces confidence interval plots for a calibration curve and provides information about the number of standard solutions, concentration levels and suitable concentration ranges to achieve an optimum calibration. Some examples of the application of this novel computational program are given, using both simulated and real data.
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spelling pubmed-25481432008-10-16 Effects of experimental design on calibration curve precision in routine analysis Pimentel, Maria Fernanda Neto, Benício de Barros Saldanha, Teresa Cristina B. Araújo, Mário César Ugulino J Automat Chem Research Article A computational program which compares the effciencies of different experimental designs with those of maximum precision (D-optimized designs) is described. The program produces confidence interval plots for a calibration curve and provides information about the number of standard solutions, concentration levels and suitable concentration ranges to achieve an optimum calibration. Some examples of the application of this novel computational program are given, using both simulated and real data. Hindawi Publishing Corporation 1998 /pmc/articles/PMC2548143/ /pubmed/18924816 http://dx.doi.org/10.1155/S1463924698000029 Text en Copyright © 1998 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Pimentel, Maria Fernanda
Neto, Benício de Barros
Saldanha, Teresa Cristina B.
Araújo, Mário César Ugulino
Effects of experimental design on calibration curve precision in routine analysis
title Effects of experimental design on calibration curve precision in routine analysis
title_full Effects of experimental design on calibration curve precision in routine analysis
title_fullStr Effects of experimental design on calibration curve precision in routine analysis
title_full_unstemmed Effects of experimental design on calibration curve precision in routine analysis
title_short Effects of experimental design on calibration curve precision in routine analysis
title_sort effects of experimental design on calibration curve precision in routine analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2548143/
https://www.ncbi.nlm.nih.gov/pubmed/18924816
http://dx.doi.org/10.1155/S1463924698000029
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