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Analysis of HIV Protease Killing Through Caspase 8 Reveals a Novel Interaction Between Caspase 8 and Mitochondria
Human Immunodeficiency Virus (HIV) protease initiates apoptosis of HIV-infected cells by proteolytic cleavage of procaspase 8, creating a novel peptide termed casp8p41. Expression of casp8p41 alone is sufficient to initiate caspase-dependent cell death associated with mitochondrial depolarization. S...
Autores principales: | Algeciras-Schimnich, Alicia, Belzacq-Casagrande, Anne-Sophie, Bren, Gary D, Nie, Zilin, Taylor, Julie A, Rizza, Stacey A, Brenner, Catherine, Badley, Andrew D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers Ltd.
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2548302/ https://www.ncbi.nlm.nih.gov/pubmed/18818773 http://dx.doi.org/10.2174/1874357900701010039 |
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