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Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR
BACKGROUND: To date, only few compounds targeting the AI-2 based quorum sensing (QS) system are known. In the present study, we screened cinnamaldehyde and substituted cinnamaldehydes for their ability to interfere with AI-2 based QS. The mechanism of QS inhibition was elucidated by measuring the ef...
Autores principales: | Brackman, Gilles, Defoirdt, Tom, Miyamoto, Carol, Bossier, Peter, Van Calenbergh, Serge, Nelis, Hans, Coenye, Tom |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551610/ https://www.ncbi.nlm.nih.gov/pubmed/18793453 http://dx.doi.org/10.1186/1471-2180-8-149 |
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