Cargando…

Metabolism-Independent Sugar Sensing in Central Orexin Neurons

OBJECTIVE— Glucose sensing by specialized neurons of the hypothalamus is vital for normal energy balance. In many glucose-activated neurons, glucose metabolism is considered a critical step in glucose sensing, but whether glucose-inhibited neurons follow the same strategy is unclear. Orexin/hypocret...

Descripción completa

Detalles Bibliográficos
Autores principales:	González, J. Antonio, Jensen, Lise T., Fugger, Lars, Burdakov, Denis
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551664/ https://www.ncbi.nlm.nih.gov/pubmed/18591392 http://dx.doi.org/10.2337/db08-0548

Ejemplares similares

Inhibitory Interplay between Orexin Neurons and Eating
por: González, J. Antonio, et al.
Publicado: (2016)

Orexin neuron activity in mating mice - a pilot study
por: Burdakov, Denis, et al.
Publicado: (2021)

Orexin/Hypocretin and MCH Neurons: Cognitive and Motor Roles Beyond Arousal
por: Concetti, Cristina, et al.
Publicado: (2021)

Control and coding of pupil size by hypothalamic orexin neurons
por: Grujic, Nikola, et al.
Publicado: (2023)

Anticipatory countering of motor challenges by premovement activation of orexin neurons
por: Donegan, Dane, et al.
Publicado: (2022)

Coreleased Orexin and Glutamate Evoke Nonredundant Spike Outputs and Computations in Histamine Neurons
por: Schöne, Cornelia, et al.
Publicado: (2014)

Awake dynamics and brain-wide direct inputs of hypothalamic MCH and orexin networks
por: González, J. Antonio, et al.
Publicado: (2016)

Cellular activation of hypothalamic hypocretin/orexin neurons facilitates short-term spatial memory in mice
por: Aitta-aho, Teemu, et al.
Publicado: (2016)

Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice
por: Chowdhury, Srikanta, et al.
Publicado: (2019)

Role of spontaneous and sensory orexin network dynamics in rapid locomotion initiation
por: Karnani, Mahesh M., et al.
Publicado: (2020)

Central α-Klotho Suppresses NPY/AgRP Neuron Activity and Regulates Metabolism in Mice
por: Landry, Taylor, et al.
Publicado: (2020)

Identification of Hypothalamic Glucoregulatory Neurons That Sense and Respond to Changes in Glycemia
por: Deem, Jennifer D., et al.
Publicado: (2023)

Orexin and MCH neurons: regulators of sleep and metabolism
por: Bouâouda, Hanan, et al.
Publicado: (2023)

Orexin, orexin receptor antagonists and central cardiovascular control
por: Carrive, Pascal
Publicado: (2013)

Regulation of Hypothalamic Neuronal Sensing and Food Intake by Ketone Bodies and Fatty Acids
por: Le Foll, Christelle, et al.
Publicado: (2014)

Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia
por: Futatsuki, Takahiro, et al.
Publicado: (2018)

Role of Central Nervous System Glucagon-Like Peptide-1 Receptors in Enteric Glucose Sensing
por: Knauf, Claude, et al.
Publicado: (2008)

Predictive models of glucose control: roles for glucose-sensing neurones
por: Kosse, C., et al.
Publicado: (2014)

Hypothalamic Nutrient Sensing Activates a Forebrain-Hindbrain Neuronal Circuit to Regulate Glucose Production In Vivo
por: Lam, Carol K.L., et al.
Publicado: (2011)

Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons
por: Farias Quipildor, Gabriela, et al.
Publicado: (2021)

Hypoglycemia-Sensing Neurons of the Ventromedial Hypothalamus Require AMPK-Induced Txn2 Expression but Are Dispensable for Physiological Counterregulation
por: Quenneville, Simon, et al.
Publicado: (2020)

High serum selenium levels are associated with increased risk for diabetes mellitus independent of central obesity and insulin resistance
por: Lu, Chia-Wen, et al.
Publicado: (2016)

Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity
por: Turku, Ainoleena, et al.
Publicado: (2017)

Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear
por: Dustrude, Erik T., et al.
Publicado: (2018)

Anorexia and Impaired Glucose Metabolism in Mice With Hypothalamic Ablation of Glut4 Neurons
por: Ren, Hongxia, et al.
Publicado: (2015)

Interaction Between the Central and Peripheral Effects of Insulin in Controlling Hepatic Glucose Metabolism in the Conscious Dog
por: Ramnanan, Christopher J., et al.
Publicado: (2013)

Orexin Neurons Receive Glycinergic Innervations
por: Hondo, Mari, et al.
Publicado: (2011)

A Major Role for Perifornical Orexin Neurons in the Control of Glucose Metabolism in Rats
por: Yi, Chun-Xia, et al.
Publicado: (2009)

Sugar is not always sweet: exploring the relationship between hyperglycemia and COVID-19 in a predominantly African American population
por: Skwiersky, Samara, et al.
Publicado: (2022)

Ghrelin Infusion in Humans Induces Acute Insulin Resistance and Lipolysis Independent of Growth Hormone Signaling
por: Vestergaard, Esben Thyssen, et al.
Publicado: (2008)

Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors
por: Heppner, Kristy M., et al.
Publicado: (2014)

VEGF-A–Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4–Independent Metabolic Improvements
por: Park, Jiyoung, et al.
Publicado: (2017)

Activity of putative orexin neurons during cataplexy
por: Zhou, Shi, et al.
Publicado: (2022)

Orexin neurons inhibit sleep to promote arousal
por: De Luca, Roberto, et al.
Publicado: (2022)

Neuromodulation of orexin neurons reduces diet-induced adiposity
por: Zink, A N, et al.
Publicado: (2018)

Circadian and dark-pulse activation of orexin/hypocretin neurons
por: Marston, Oliver J, et al.
Publicado: (2008)

Glutamate and GABA as rapid effectors of hypothalamic “peptidergic” neurons
por: Schöne, Cornelia, et al.
Publicado: (2012)

A genetically encoded sensor for in vivo imaging of orexin neuropeptides
por: Duffet, Loïc, et al.
Publicado: (2022)

Impact of Physical Inactivity on Subcutaneous Adipose Tissue Metabolism in Healthy Young Male Offspring of Patients With Type 2 Diabetes
por: Højbjerre, Lise, et al.
Publicado: (2010)

Orexin Neurons Contribute to Central Modulation of Respiratory Drive by Progestins on ex vivo Newborn Rodent Preparations
por: Loiseau, Camille, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jruuiu73v4g32r24eba9j37jsn