Cargando…

Baseline Serum 25-Hydroxy Vitamin D Is Predictive of Future Glycemic Status and Insulin Resistance : The Medical Research Council Ely Prospective Study 1990–2000

OBJECTIVE—Accumulating epidemiological evidence suggests that hypovitaminosis D may be associated with type 2 diabetes and related metabolic risks. However, prospective data using the biomarker serum 25-hydroxyvitamin D [25(OH)D] are limited and therefore examined in the present study. RESEARCH DESI...

Descripción completa

Detalles Bibliográficos
Autores principales:	Forouhi, Nita G., Luan, Jian'an, Cooper, Andrew, Boucher, Barbara J., Wareham, Nicholas J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551670/ https://www.ncbi.nlm.nih.gov/pubmed/18591391 http://dx.doi.org/10.2337/db08-0593

Ejemplares similares

α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid (AMPA) and N-Methyl-d-aspartate (NMDA) Receptors Adopt Different Subunit Arrangements
por: Balasuriya, Dilshan, et al.
Publicado: (2013)

Palmitoylation Targets AKAP79 Protein to Lipid Rafts and Promotes Its Regulation of Calcium-sensitive Adenylyl Cyclase Type 8
por: Delint-Ramirez, Ilse, et al.
Publicado: (2011)

AKAP79/150 Interacts with AC8 and Regulates Ca(2+)-dependent cAMP Synthesis in Pancreatic and Neuronal Systems
por: Willoughby, Debbie, et al.
Publicado: (2010)

Small Molecule AKAP-Protein Kinase A (PKA) Interaction Disruptors That Activate PKA Interfere with Compartmentalized cAMP Signaling in Cardiac Myocytes
por: Christian, Frank, et al.
Publicado: (2011)

Mechanism of Oxidative DNA Damage in Diabetes : Tuberin Inactivation and Downregulation of DNA Repair Enzyme 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine-DNA Glycosylase
por: Simone, Simona, et al.
Publicado: (2008)

Integrin-Associated Protein Association With Src Homology 2 Domain Containing Tyrosine Phosphatase Substrate 1 Regulates IGF-I Signaling In Vivo
por: Maile, Laura A., et al.
Publicado: (2008)

Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle
por: Morino, Katsutaro, et al.
Publicado: (2008)

Forkhead Transcription Factors (FoxOs) Promote Apoptosis of Insulin-Resistant Macrophages During Cholesterol-Induced Endoplasmic Reticulum Stress
por: Senokuchi, Takafumi, et al.
Publicado: (2008)

Human Adenovirus Type 36 Enhances Glucose Uptake in Diabetic and Nondiabetic Human Skeletal Muscle Cells Independent of Insulin Signaling
por: Wang, Zhong Q., et al.
Publicado: (2008)

Activation of Estrogen Receptor Is Crucial for Resveratrol-Stimulating Muscular Glucose Uptake via Both Insulin-Dependent and -Independent Pathways
por: Deng, Jen-Ying, et al.
Publicado: (2008)

siRNA-Mediated Reduction of Inhibitor of Nuclear Factor-κB Kinase Prevents Tumor Necrosis Factor-α–Induced Insulin Resistance in Human Skeletal Muscle
por: Austin, Reginald L., et al.
Publicado: (2008)

Autocrine IGF-1 Action in Adipocytes Controls Systemic IGF-1 Concentrations and Growth
por: Klöting, Nora, et al.
Publicado: (2008)

Metabolically Favorable Remodeling of Human Adipose Tissue by Human Adenovirus Type 36
por: Rogers, Pamela M., et al.
Publicado: (2008)

Impact of Oxidative Stress and Peroxisome Proliferator–Activated Receptor γ Coactivator-1α in Hepatic Insulin Resistance
por: Kumashiro, Naoki, et al.
Publicado: (2008)

Hypoxia Decreases Insulin Signaling Pathways in Adipocytes
por: Regazzetti, Claire, et al.
Publicado: (2009)

Dual Role of Interleukin-6 in Regulating Insulin Sensitivity in Murine Skeletal Muscle
por: Nieto-Vazquez, Iria, et al.
Publicado: (2008)

Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes
por: Xie, Zhonglin, et al.
Publicado: (2008)

Differential Distribution, Clustering, and Lateral Diffusion of Subtypes of the Inositol 1,4,5-Trisphosphate Receptor
por: Pantazaka, Evangelia, et al.
Publicado: (2011)

Hydrophobic Motif Phosphorylation Is Not Required for Activation Loop Phosphorylation of p70 Ribosomal Protein S6 Kinase 1 (S6K1)
por: Keshwani, Malik M., et al.
Publicado: (2011)

Submaximal Inhibition of Protein Kinase C Restores ADP-induced Dense Granule Secretion in Platelets in the Presence of Ca(2+)
por: Unsworth, Amanda J., et al.
Publicado: (2011)

Anchored Protein Kinase A Recruitment of Active Rac GTPase
por: Logue, Jeremy S., et al.
Publicado: (2011)

Klotho Depletion Contributes to Increased Inflammation in Kidney of the db/db Mouse Model of Diabetes via RelA (Serine)(536) Phosphorylation
por: Zhao, Yanhua, et al.
Publicado: (2011)

Endothelin-1 (ET-1) Increases the Expression of Remodeling Genes in Vascular Smooth Muscle through Linked Calcium and cAMP Pathways: ROLE OF A PHOSPHOLIPASE A(2)(cPLA(2))/CYCLOOXYGENASE-2 (COX-2)/PROSTACYCLIN RECEPTOR-DEPENDENT AUTOCRINE LOOP
por: Deacon, Karl, et al.
Publicado: (2010)

Cross-talk between the p38α and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation
por: Staples, Christopher J., et al.
Publicado: (2010)

A New Pathway of CD5 Glycoprotein-mediated T Cell Inhibition Dependent on Inhibitory Phosphorylation of Fyn Kinase
por: Bamberger, Martina, et al.
Publicado: (2011)

Identification of Human P2X1 Receptor-interacting Proteins Reveals a Role of the Cytoskeleton in Receptor Regulation
por: Lalo, Ulyana, et al.
Publicado: (2011)

Negative Regulation of TGFβ Signaling by the Kinase LKB1 and the Scaffolding Protein LIP1
por: Morén, Anita, et al.
Publicado: (2011)

Phosphatidylinositol-4-Phosphate-5-Kinase α Deficiency Alters Dynamics of Glucose-Stimulated Insulin Release to Improve Glucohomeostasis and Decrease Obesity in Mice
por: Huang, Ping, et al.
Publicado: (2011)

Cysteine Scanning Mutagenesis (Residues Glu(52)–Gly(96)) of the Human P2X1 Receptor for ATP: MAPPING AGONIST BINDING AND CHANNEL GATING
por: Allsopp, Rebecca C., et al.
Publicado: (2011)

Signal Integration and Coincidence Detection in the Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Cascade: CONCOMITANT ACTIVATION OF RECEPTOR TYROSINE KINASES AND OF LRP-1 LEADS TO SUSTAINED ERK PHOSPHORYLATION VIA DOWN-REGULATION OF DUAL SPECIFICITY PHOSPHATASES (DUSP1 AND -6)
por: Geetha, Nishamol, et al.
Publicado: (2011)

Insulin Growth Factor-2 Binding Protein 3 (IGF2BP3) Is a Glioblastoma-specific Marker That Activates Phosphatidylinositol 3-Kinase/Mitogen-activated Protein Kinase (PI3K/MAPK) Pathways by Modulating IGF-2
por: Suvasini, Ramaswamy, et al.
Publicado: (2011)

mTORC2 Protein-mediated Protein Kinase B (Akt) Serine 473 Phosphorylation Is Not Required for Akt1 Activity in Human Platelets
por: Moore, Samantha F., et al.
Publicado: (2011)

Molecular Determinants within N Terminus of Orai3 Protein That Control Channel Activation and Gating
por: Bergsmann, Judith, et al.
Publicado: (2011)

RB1CC1 Protein Positively Regulates Transforming Growth Factor-β Signaling through the Modulation of Arkadia E3 Ubiquitin Ligase Activity
por: Koinuma, Daizo, et al.
Publicado: (2011)

Uncoupling Protein 3 (UCP3) Modulates the Activity of Sarco/Endoplasmic Reticulum Ca(2+)-ATPase (SERCA) by Decreasing Mitochondrial ATP Production
por: De Marchi, Umberto, et al.
Publicado: (2011)

Insulin Restores Gestational Diabetes Mellitus–Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium
por: Westermeier, Francisco, et al.
Publicado: (2011)

Cross-Talk Between Interferon-γ and Hedgehog Signaling Regulates Adipogenesis
por: Todoric, Jelena, et al.
Publicado: (2011)

Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network
por: Lagathu, Claire, et al.
Publicado: (2009)

Protein Kinase A Regulatory Subunits in Human Adipose Tissue: Decreased R2B Expression and Activity in Adipocytes From Obese Subjects
por: Mantovani, Giovanna, et al.
Publicado: (2009)

Novel Insights into the Cellular Mechanisms of the Anti-inflammatory Effects of NF-κB Essential Modulator Binding Domain Peptides
por: Baima, Eric T., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_8h0grkhu3hmormr1ueegcga9p1