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Postnatal Expansion of the Pancreatic β-Cell Mass Is Dependent on Survivin

OBJECTIVE—Diabetes results from a deficiency of functional β-cells due to both an increase in β-cell death and an inhibition of β-cell replication. The molecular mechanisms responsible for these effects in susceptible individuals are mostly unknown. The objective of this study was to determine wheth...

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Detalles Bibliográficos
Autores principales: Jiang, Yuying, Nishimura, Wataru, Devor-Henneman, Deborah, Kusewitt, Donna, Wang, Haijuan, Holloway, Michael P., Dohi, Takehiko, Sabo, Edmond, Robinson, Michael L., Altieri, Dario C., Sharma, Arun, Altura, Rachel A.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551682/
https://www.ncbi.nlm.nih.gov/pubmed/18599523
http://dx.doi.org/10.2337/db08-0170