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Resting Regulatory CD4 T Cells: A Site of HIV Persistence in Patients on Long-Term Effective Antiretroviral Therapy

BACKGROUND: In HIV-infected patients on long-term HAART, virus persistence in resting long-lived CD4 T cells is a major barrier to curing the infection. Cell quiescence, by favouring HIV latency, reduces the risk of recognition and cell destruction by cytotoxic lymphocytes. Several cell-activation-b...

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Detalles Bibliográficos
Autores principales: Tran, Tu-Anh, de Goër de Herve, Marie-Ghislaine, Hendel-Chavez, Houria, Dembele, Bamory, Le Névot, Emilie, Abbed, Karim, Pallier, Coralie, Goujard, Cécile, Gasnault, Jacques, Delfraissy, Jean-François, Balazuc, Anne-Marie, Taoufik, Yassine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551739/
https://www.ncbi.nlm.nih.gov/pubmed/18827929
http://dx.doi.org/10.1371/journal.pone.0003305

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