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Novel genome polymorphisms in BCG vaccine strains and impact on efficacy

Bacille Calmette-Guérin (BCG) is an attenuated strain of Mycobacterium bovis currently used as a vaccine against tuberculosis. Global distribution and propagation of BCG has contributed to the in vitro evolution of the vaccine strain and is thought to partially account for the different outcomes of...

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Detalles Bibliográficos
Autores principales:	Leung, Andrea S, Tran, Vanessa, Wu, Zuowei, Yu, Xuping, Alexander, David C, Gao, George Fu, Zhu, Baoli, Liu, Jun
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553098/ https://www.ncbi.nlm.nih.gov/pubmed/18793412 http://dx.doi.org/10.1186/1471-2164-9-413

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