Cargando…
Evolution of the Aging Brain Transcriptome and Synaptic Regulation
Alzheimer's disease and other neurodegenerative disorders of aging are characterized by clinical and pathological features that are relatively specific to humans. To obtain greater insight into how brain aging has evolved, we compared age-related gene expression changes in the cortex of humans,...
Autores principales: | Loerch, Patrick M., Lu, Tao, Dakin, Kelly A., Vann, James M., Isaacs, Adrian, Geula, Chengiz, Wang, Jianbin, Pan, Ying, Gabuzda, Dana H., Li, Cheng, Prolla, Tomas A., Yankner, Bruce A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553198/ https://www.ncbi.nlm.nih.gov/pubmed/18830410 http://dx.doi.org/10.1371/journal.pone.0003329 |
Ejemplares similares
-
Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment
por: Guha, Debjani, et al.
Publicado: (2019) -
Neuronal Excitatory State Is Linked to Stress Resilience
por: Zullo, Joseph, et al.
Publicado: (2021) -
Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms
por: Lorenz, David R., et al.
Publicado: (2019) -
The evolution of synaptic and cognitive capacity: Insights from the nervous system transcriptome of Aplysia
por: Orvis, Joshua, et al.
Publicado: (2022) -
Dendritic spinule-mediated structural synaptic plasticity: Implications for development, aging, and psychiatric disease
por: Zaccard, Colleen R., et al.
Publicado: (2023)