Activation of the Unfolded Protein Response Is Required for Defenses against Bacterial Pore-Forming Toxin In Vivo

Pore-forming toxins (PFTs) constitute the single largest class of proteinaceous bacterial virulence factors and are made by many of the most important bacterial pathogens. Host responses to these toxins are complex and poorly understood. We find that the endoplasmic reticulum unfolded protein respon...

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Detalles Bibliográficos
Autores principales: Bischof, Larry J., Kao, Cheng-Yuan, Los, Ferdinand C. O., Gonzalez, Manuel R., Shen, Zhouxin, Briggs, Steven P., van der Goot, F. Gisou, Aroian, Raffi V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553261/
https://www.ncbi.nlm.nih.gov/pubmed/18846208
http://dx.doi.org/10.1371/journal.ppat.1000176

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