Cargando…
Phosphorylation of p130Cas initiates Rac activation and membrane ruffling
BACKGROUND: Non-receptor tyrosine kinases (NTKs) regulate physiological processes such as cell migration, differentiation, proliferation, and survival by interacting with and phosphorylating a large number of substrates simultaneously. This makes it difficult to attribute a particular biological eff...
Autores principales: | Sharma, Alok, Mayer, Bruce J |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553404/ https://www.ncbi.nlm.nih.gov/pubmed/18793427 http://dx.doi.org/10.1186/1471-2121-9-50 |
Ejemplares similares
-
Rac1 activation can generate untemplated, lamellar membrane ruffles
por: Leyden, F., et al.
Publicado: (2021) -
Requirements for Both Rac1 and Cdc42 in Membrane Ruffling and Phagocytosis in Leukocytes
por: Cox, Dianne, et al.
Publicado: (1997) -
EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42
por: Bulgin, Richard R, et al.
Publicado: (2009) -
DOCK9 induces membrane ruffles and Rac1 activity in cancer HeLa epithelial cells
por: Ruiz-Lafuente, Natalia, et al.
Publicado: (2018) -
uPAR promotes formation of the p130Cas–Crk complex to activate Rac through DOCK180
por: Smith, Harvey W., et al.
Publicado: (2008)