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Phylogenetic analysis of mRNA polyadenylation sites reveals a role of transposable elements in evolution of the 3′-end of genes

mRNA polyadenylation is an essential step for the maturation of almost all eukaryotic mRNAs, and is tightly coupled with termination of transcription in defining the 3′-end of genes. Large numbers of human and mouse genes harbor alternative polyadenylation sites [poly(A) sites] that lead to mRNA var...

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Detalles Bibliográficos
Autores principales:	Lee, Ju Youn, Ji, Zhe, Tian, Bin
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553571/ https://www.ncbi.nlm.nih.gov/pubmed/18757892 http://dx.doi.org/10.1093/nar/gkn540

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