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Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage

The enzyme ribonucleotide reductase, responsible for the synthesis of deoxyribonucleotides (dNTP), is upregulated in response to DNA damage in all organisms. In Saccharomyces cerevisiae, dNTP concentration increases ∼6- to 8-fold in response to DNA damage. This concentration increase is associated w...

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Detalles Bibliográficos
Autores principales:	Sabouri, Nasim, Viberg, Jörgen, Goyal, Dinesh Kumar, Johansson, Erik, Chabes, Andrei
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553575/ https://www.ncbi.nlm.nih.gov/pubmed/18772226 http://dx.doi.org/10.1093/nar/gkn555

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