Cargando…

Thermodynamic analysis of 5′ and 3′ single- and 3′ double-nucleotide overhangs neighboring wobble terminal base pairs

Thermodynamic parameters are reported for duplex formation of 40 self-complementary RNA duplexes containing wobble terminal base pairs with all possible 3′ single and double-nucleotide overhangs, mimicking the structures of short interfering RNAs (siRNA) and microRNAs (miRNA). Based on nearest neigh...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Stacy, Jones, Laura E., Giovannitti, Karen, Piper, Dan, Serra, Martin J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553593/
https://www.ncbi.nlm.nih.gov/pubmed/18765476
http://dx.doi.org/10.1093/nar/gkn525