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Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism
BACKGROUND: Septic encephalopathy is a severe brain dysfunction caused by systemic inflammation in the absence of direct brain infection. Changes in cerebral blood flow, release of inflammatory molecules and metabolic alterations contribute to neuronal dysfunction and cell death. METHODS: To investi...
Autores principales: | Semmler, Alexander, Hermann, Sven, Mormann, Florian, Weberpals, Marc, Paxian, Stephan A, Okulla, Thorsten, Schäfers, Michael, Kummer, Markus P, Klockgether, Thomas, Heneka, Michael T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553764/ https://www.ncbi.nlm.nih.gov/pubmed/18793399 http://dx.doi.org/10.1186/1742-2094-5-38 |
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