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Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature
BACKGROUND: Acral lentiginous melanoma (ALM) is an uncommon, cutaneous malignant tumour which may arise on the foot. Its relative rarity, atypical appearance and late presentation frequently serve as poor prognostic indicators. METHODS: At a tertiary skin tumour centre, a retrospective review was un...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553782/ https://www.ncbi.nlm.nih.gov/pubmed/18822168 http://dx.doi.org/10.1186/1757-1146-1-11 |
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author | Bristow, Ivan R Acland, Katharine |
author_facet | Bristow, Ivan R Acland, Katharine |
author_sort | Bristow, Ivan R |
collection | PubMed |
description | BACKGROUND: Acral lentiginous melanoma (ALM) is an uncommon, cutaneous malignant tumour which may arise on the foot. Its relative rarity, atypical appearance and late presentation frequently serve as poor prognostic indicators. METHODS: At a tertiary skin tumour centre, a retrospective review was undertaken of all patients diagnosed with the tumour at the level of ankle or below. RESULTS: Over a six year period, 27 cases (20 female, 7 male) were identified with positive histology confirming the disease. The age ranged from 35–96 years of age (mean 62.7 years). The majority of the cohort were white (59%) with plantar lesions (62%). 33% of patients were initially were diagnosed incorrectly. The average time taken from the point of recognition, by the patient, to the lesion being correctly diagnosed was around 13.5 months. CONCLUSION: Earlier diagnosis of ALM requires education at both a patient and practitioner level. |
format | Text |
id | pubmed-2553782 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-25537822008-09-27 Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature Bristow, Ivan R Acland, Katharine J Foot Ankle Res Research BACKGROUND: Acral lentiginous melanoma (ALM) is an uncommon, cutaneous malignant tumour which may arise on the foot. Its relative rarity, atypical appearance and late presentation frequently serve as poor prognostic indicators. METHODS: At a tertiary skin tumour centre, a retrospective review was undertaken of all patients diagnosed with the tumour at the level of ankle or below. RESULTS: Over a six year period, 27 cases (20 female, 7 male) were identified with positive histology confirming the disease. The age ranged from 35–96 years of age (mean 62.7 years). The majority of the cohort were white (59%) with plantar lesions (62%). 33% of patients were initially were diagnosed incorrectly. The average time taken from the point of recognition, by the patient, to the lesion being correctly diagnosed was around 13.5 months. CONCLUSION: Earlier diagnosis of ALM requires education at both a patient and practitioner level. BioMed Central 2008-09-15 /pmc/articles/PMC2553782/ /pubmed/18822168 http://dx.doi.org/10.1186/1757-1146-1-11 Text en Copyright © 2008 Bristow and Acland; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Bristow, Ivan R Acland, Katharine Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature |
title | Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature |
title_full | Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature |
title_fullStr | Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature |
title_full_unstemmed | Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature |
title_short | Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature |
title_sort | acral lentiginous melanoma of the foot and ankle: a case series and review of the literature |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553782/ https://www.ncbi.nlm.nih.gov/pubmed/18822168 http://dx.doi.org/10.1186/1757-1146-1-11 |
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