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Glucosamine increases hyaluronic acid production in human osteoarthritic synovium explants

BACKGROUND: Glucosamine (GlcN) used by patients with osteoarthritis was demonstrated to reduce pain, but the working mechanism is still not clear. Viscosupplementation with hyaluronic acid (HA) is also described to reduce pain in osteoarthritis. The synthesis of HA requires GlcN as one of its main b...

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Detalles Bibliográficos
Autores principales:	Uitterlinden, EJ, Koevoet, JLM, Verkoelen, CF, Bierma-Zeinstra, SMA, Jahr, H, Weinans, H, Verhaar, JAN, van Osch, GJVM
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553787/ https://www.ncbi.nlm.nih.gov/pubmed/18786270 http://dx.doi.org/10.1186/1471-2474-9-120

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