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Functional analyses reveal an important role for tyrosine residues in the staphylococcal multidrug efflux protein QacA

BACKGROUND: The staphylococcal QacA multidrug efflux protein confers resistance to an exceptional number of structurally unrelated antimicrobial compounds. Aromatic amino acid residues have been shown to be highly important for the transport function of several multidrug transporters and are intimat...

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Detalles Bibliográficos
Autores principales: Wu, Jingqin, Hassan, Karl A, Skurray, Ronald A, Brown, Melissa H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553796/
https://www.ncbi.nlm.nih.gov/pubmed/18793443
http://dx.doi.org/10.1186/1471-2180-8-147