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Functional analyses reveal an important role for tyrosine residues in the staphylococcal multidrug efflux protein QacA
BACKGROUND: The staphylococcal QacA multidrug efflux protein confers resistance to an exceptional number of structurally unrelated antimicrobial compounds. Aromatic amino acid residues have been shown to be highly important for the transport function of several multidrug transporters and are intimat...
Autores principales: | Wu, Jingqin, Hassan, Karl A, Skurray, Ronald A, Brown, Melissa H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553796/ https://www.ncbi.nlm.nih.gov/pubmed/18793443 http://dx.doi.org/10.1186/1471-2180-8-147 |
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