A Novel Role for the SMG-1 Kinase in Lifespan and Oxidative Stress Resistance in Caenorhabditis elegans

The PTEN tumour suppressor encodes a phosphatase, and its daf-18 orthologue in Caenorhabditis elegans negatively regulates the insulin/IGF-1 DAF-2 receptor pathway that influences lifespan in worms and other species. In order to identify new DAF-18 regulated pathways involved in aging, we initiated...

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Detalles Bibliográficos
Autores principales: Masse, Ingrid, Molin, Laurent, Mouchiroud, Laurent, Vanhems, Philippe, Palladino, Francesca, Billaud, Marc, Solari, Florence
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556085/
https://www.ncbi.nlm.nih.gov/pubmed/18836529
http://dx.doi.org/10.1371/journal.pone.0003354

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