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A Single CD8(+) T Cell Epitope Sets the Long-Term Latent Load of a Murid Herpesvirus
The pathogenesis of persistent viral infections depends critically on long-term viral loads. Yet what determines these loads is largely unknown. Here, we show that a single CD8(+) T cell epitope sets the long-term latent load of a lymphotropic gamma-herpesvirus, Murid herpesvirus-4 (MuHV-4). The MuH...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556087/ https://www.ncbi.nlm.nih.gov/pubmed/18846211 http://dx.doi.org/10.1371/journal.ppat.1000177 |