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Turning of the receptor-binding domains opens up the murine leukaemia virus Env for membrane fusion

The activity of the membrane fusion protein Env of Moloney mouse leukaemia virus is controlled by isomerization of the disulphide that couples its transmembrane (TM) and surface (SU) subunits. We have arrested Env activation at a stage prior to isomerization by alkylating the active thiol in SU and...

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Detalles Bibliográficos
Autores principales:	Wu, Shang-Rung, Sjöberg, Mathilda, Wallin, Michael, Lindqvist, Birgitta, Ekström, Maria, Hebert, Hans, Koeck, Philip J B, Garoff, Henrik
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556092/ https://www.ncbi.nlm.nih.gov/pubmed/18800055 http://dx.doi.org/10.1038/emboj.2008.187

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