Cargando…

High Throughput Selection of Effective Serodiagnostics for Trypanosoma cruzi infection

BACKGROUND: Diagnosis of Trypanosoma cruzi infection by direct pathogen detection is complicated by the low parasite burden in subjects persistently infected with this agent of human Chagas disease. Determination of infection status by serological analysis has also been faulty, largely due to the la...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cooley, Gretchen, Etheridge, R. Drew, Boehlke, Courtney, Bundy, Becky, Weatherly, D. Brent, Minning, Todd, Haney, Matthew, Postan, Miriam, Laucella, Susana, Tarleton, Rick L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556098/ https://www.ncbi.nlm.nih.gov/pubmed/18841200 http://dx.doi.org/10.1371/journal.pntd.0000316

Ejemplares similares

Chromosome level assembly of the hybrid Trypanosoma cruzi genome
por: Weatherly, D Brent, et al.
Publicado: (2009)

The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi
por: Minning, Todd A, et al.
Publicado: (2009)

Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridization
por: Minning, Todd A, et al.
Publicado: (2011)

CD8(+) T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes
por: Martin, Diana L, et al.
Publicado: (2006)

Recombination-driven generation of the largest pathogen repository of antigen variants in the protozoan Trypanosoma cruzi
por: Weatherly, D. Brent, et al.
Publicado: (2016)

In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds
por: Canavaci, Adriana M. C., et al.
Publicado: (2010)

Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses
por: Alvarez, María G., et al.
Publicado: (2016)

The Significance of Discordant Serology in Chagas Disease: Enhanced T-Cell Immunity to Trypanosoma cruzi in Serodiscordant Subjects
por: Castro Eiro, Melisa D., et al.
Publicado: (2017)

CRISPR-Cas9-Mediated Single-Gene and Gene Family Disruption in Trypanosoma cruzi
por: Peng, Duo, et al.
Publicado: (2014)

Frequency of IFNγ-producing T cells correlates with seroreactivity and activated T cells during canine Trypanosoma cruzi infection
por: Hartley, Ashley N, et al.
Publicado: (2014)

Inhibitory Receptors Are Expressed by Trypanosoma cruzi-Specific Effector T Cells and in Hearts of Subjects with Chronic Chagas Disease
por: Argüello, Rafael J., et al.
Publicado: (2012)

Distinct Treatment Outcomes of Antiparasitic Therapy in Trypanosoma cruzi-Infected Children Is Associated With Early Changes in Cytokines, Chemokines, and T-Cell Phenotypes
por: Albareda, María C., et al.
Publicado: (2018)

A Semantic Problem Solving Environment for Integrative Parasite Research: Identification of Intervention Targets for Trypanosoma cruzi
por: Parikh, Priti P., et al.
Publicado: (2012)

HLA Class I-T Cell Epitopes from trans-Sialidase Proteins Reveal Functionally Distinct Subsets of CD8(+) T Cells in Chronic Chagas Disease
por: Alvarez, María G., et al.
Publicado: (2008)

Modulation of Trypanosoma cruzi-specific T-cell responses after chemotherapy for chronic Chagas disease
por: Albareda, María Cecilia, et al.
Publicado: (2015)

Evaluation of high efficiency gene knockout strategies for Trypanosoma cruzi
por: Xu, Dan, et al.
Publicado: (2009)

Reaching for the Holy Grail: insights from infection/cure models on the prospects for vaccines for Trypanosoma cruzi infection
por: Bustamante, Juan, et al.
Publicado: (2015)

Polyfunctional T Cell Responses in Children in Early Stages of Chronic Trypanosoma cruzi Infection Contrast with Monofunctional Responses of Long-term Infected Adults
por: Albareda, María C., et al.
Publicado: (2013)

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure
por: Sánchez-Valdéz, Fernando J, et al.
Publicado: (2018)

High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive non-human primate breeding colony in Texas, USA
por: Padilla, Angel M., et al.
Publicado: (2021)

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease
por: Wang, Wei, et al.
Publicado: (2021)

TcruziDB: an integrated, post-genomics community resource for Trypanosoma cruzi
por: Agüero, Fernán, et al.
Publicado: (2006)

Identification of Contractile Vacuole Proteins in Trypanosoma cruzi
por: Ulrich, Paul N., et al.
Publicado: (2011)

Identification and Localization of the First Known Proteins of the Trypanosoma cruzi Cytostome Cytopharynx Endocytic Complex
por: Chasen, Nathan Michael, et al.
Publicado: (2020)

Elucidating the 3D Structure of a Surface Membrane Antigen from Trypanosoma cruzi as a Serodiagnostic Biomarker of Chagas Disease
por: Di Pisa, Flavio, et al.
Publicado: (2022)

The Functional Characterization of TcMyoF Implicates a Family of Cytostome-Cytopharynx Targeted Myosins as Integral to the Endocytic Machinery of Trypanosoma cruzi
por: Chasen, Nathan Michael, et al.
Publicado: (2020)

Inactive trans-Sialidase Expression in iTS-null Trypanosoma cruzi Generates Virulent Trypomastigotes
por: Pascuale, Carla A., et al.
Publicado: (2017)

Anti-inflammatory Role of Galectin-8 During Trypanosoma cruzi Chronic Infection
por: Bertelli, Adriano, et al.
Publicado: (2020)

Delayed Activation of T Cells at the Site of Infection Facilitates the Establishment of Trypanosoma cruzi in Both Naive and Immune Hosts
por: Padilla, Angel M., et al.
Publicado: (2023)

Trypanosoma cruzi Infection at the Maternal-Fetal Interface: Implications of Parasite Load in the Congenital Transmission and Challenges in the Diagnosis of Infected Newborns
por: Bustos, Patricia L., et al.
Publicado: (2019)

Highly competent, non-exhausted CD8+ T cells continue to tightly control pathogen load throughout chronic Trypanosoma cruzi infection
por: Pack, Angela D., et al.
Publicado: (2018)

TcHRG plays a central role in orchestrating heme uptake in Trypanosoma cruzi epimastigotes
por: Tevere, Evelyn, et al.
Publicado: (2023)

High Throughput Screening for Anti–Trypanosoma cruzi Drug Discovery
por: Alonso-Padilla, Julio, et al.
Publicado: (2014)

Impact of Aetiological Treatment on Conventional and Multiplex Serology in Chronic Chagas Disease
por: Viotti, Rodolfo, et al.
Publicado: (2011)

Phenotypic diversity and drug susceptibility of Trypanosoma cruzi TcV clinical isolates
por: Quebrada Palacio, Luz P., et al.
Publicado: (2018)

Knockout of the dhfr-ts Gene in Trypanosoma cruzi Generates Attenuated Parasites Able to Confer Protection against a Virulent Challenge
por: Perez Brandan, Cecilia, et al.
Publicado: (2011)

A high-throughput cloning system for reverse genetics in Trypanosoma cruzi
por: Batista, Michel, et al.
Publicado: (2010)

Trypanosoma cruzi Secreted Cyclophilin TcCyP19 as an Early Marker for Trypanocidal Treatment Efficiency
por: Perrone, Alina E., et al.
Publicado: (2023)

Serodiagnostic antigens of Clonorchis sinensis identified and evaluated by high-throughput proteogenomics
por: Cho, Pyo Yun, et al.
Publicado: (2020)

Galectin-1 Prevents Infection and Damage Induced by Trypanosoma cruzi on Cardiac Cells
por: Benatar, Alejandro F., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_anrbsf1bi1nrs4ci756tbn2sdv