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Plasticity of Drosophila Stat DNA binding shows an evolutionary basis for Stat transcription factor preferences

In vertebrates, seven signal transducer and activator of transcription (STAT) proteins bind to palindromic sites separated by spacers of two or three nucleotides (STAT1), four nucleotides (STAT6) or three nucleotides (STAT2 to STAT5a/b). This diversity of binding sites provides specificity to counte...

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Detalles Bibliográficos
Autores principales: Rivas, María Luisa, Cobreros, Laura, Zeidler, Martin P, Hombría, James Castelli-Gair
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556238/
https://www.ncbi.nlm.nih.gov/pubmed/18802449
http://dx.doi.org/10.1038/embor.2008.170