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In search of causal variants: refining disease association signals using cross-population contrasts

BACKGROUND: Genome-wide association (GWA) using large numbers of single nucleotide polymorphisms (SNPs) is now a powerful, state-of-the-art approach to mapping human disease genes. When a GWA study detects association between a SNP and the disease, this signal usually represents association with a s...

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Detalles Bibliográficos
Autores principales: Saccone, Nancy L, Saccone, Scott F, Goate, Alison M, Grucza, Richard A, Hinrichs, Anthony L, Rice, John P, Bierut, Laura J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556340/
https://www.ncbi.nlm.nih.gov/pubmed/18759969
http://dx.doi.org/10.1186/1471-2156-9-58