Cargando…
In search of causal variants: refining disease association signals using cross-population contrasts
BACKGROUND: Genome-wide association (GWA) using large numbers of single nucleotide polymorphisms (SNPs) is now a powerful, state-of-the-art approach to mapping human disease genes. When a GWA study detects association between a SNP and the disease, this signal usually represents association with a s...
Autores principales: | Saccone, Nancy L, Saccone, Scott F, Goate, Alison M, Grucza, Richard A, Hinrichs, Anthony L, Rice, John P, Bierut, Laura J |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556340/ https://www.ncbi.nlm.nih.gov/pubmed/18759969 http://dx.doi.org/10.1186/1471-2156-9-58 |
Ejemplares similares
-
Targeted sequencing identifies genetic polymorphisms of flavin‐containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American
por: Zhang, Tian‐Xiao, et al.
Publicado: (2017) -
Application of Bayesian network structure learning to identify causal variant SNPs from resequencing data
por: Schlosberg, Christopher E, et al.
Publicado: (2011) -
Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy
por: Sadler, Brooke, et al.
Publicado: (2014) -
Genetic analysis of maximum cigarette-use phenotypes
por: Saccone, Nancy L, et al.
Publicado: (2003) -
Genetic analysis of the maximum drinks phenotype
por: Saccone, Scott F, et al.
Publicado: (2005)