Identification and Replication of Three Novel Myopia Common Susceptibility Gene Loci on Chromosome 3q26 using Linkage and Linkage Disequilibrium Mapping

Refractive error is a highly heritable quantitative trait responsible for considerable morbidity. Following an initial genome-wide linkage study using microsatellite markers, we confirmed evidence for linkage to chromosome 3q26 and then conducted fine-scale association mapping using high-resolution...

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Detalles Bibliográficos
Autores principales: Andrew, Toby, Maniatis, Nikolas, Carbonaro, Francis, Liew, S. H. Melissa, Lau, Winston, Spector, Tim D., Hammond, Christopher J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556391/
https://www.ncbi.nlm.nih.gov/pubmed/18846214
http://dx.doi.org/10.1371/journal.pgen.1000220

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