Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells

Squamous cell carcinomas (SCCs) of the skin are sun-induced skin cancers that are particularly numerous in patients on T cell immunosuppression. We found that blood vessels in SCCs did not express E-selectin, and tumors contained few cutaneous lymphocyte antigen (CLA)(+) T cells, the cell type thoug...

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Autores principales: Clark, Rachael A., Huang, Susan J., Murphy, George F., Mollet, Ilse G., Hijnen, Dirkjan, Muthukuru, Manoj, Schanbacher, Carl F., Edwards, Vonetta, Miller, Danielle M., Kim, Jenny E., Lambert, Jo, Kupper, Thomas S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
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Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556796/
https://www.ncbi.nlm.nih.gov/pubmed/18794336
http://dx.doi.org/10.1084/jem.20071190

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