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Are there sensitive subgroups for the effects of airborne particles?

Recent studies have shown that particulate air pollution is a risk factor for hospitalization for heart and lung disease; however, little is known about what subpopulations are most sensitive to this pollutant. We analyzed Medicare hospital admissions for heart disease, chronic obstructive pulmonary...

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Detalles Bibliográficos
Autores principales: Zanobetti, A, Schwartz, J, Gold, D
Formato: Texto
Lenguaje:English
Publicado: 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556924/
https://www.ncbi.nlm.nih.gov/pubmed/11017888
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author Zanobetti, A
Schwartz, J
Gold, D
author_facet Zanobetti, A
Schwartz, J
Gold, D
author_sort Zanobetti, A
collection PubMed
description Recent studies have shown that particulate air pollution is a risk factor for hospitalization for heart and lung disease; however, little is known about what subpopulations are most sensitive to this pollutant. We analyzed Medicare hospital admissions for heart disease, chronic obstructive pulmonary disorders (COPD) and pneumonia in Chicago, Cook County, Illinois, between 1985 and 1994. We examined whether previous admissions or secondary diagnoses for selected conditions predisposed persons to having a greater risk from air pollution. We also considered effect modification by age, sex, and race. We found that the air-pollution-associated increase in hospital admissions for cardiovascular diseases was almost doubled in subjects with concurrent respiratory infections. The risk was also increased by a previous admission for conduction disorders. For COPD and pneumonia admissions, diagnosis of conduction disorders or dysrhythmias increased the risk of particulate matter < 10 microm in aerodynamic diameter (PM(10))-associated admissions. Persons with asthma had twice the risk of a PM(10)-associated pneumonia admission and persons with heart failure had twice the risk of PM(10)-induced COPD admissions. The PM(10) effect did not vary by sex, age, and race. These results suggest that patients with acute respiratory infections or defects in the electrical control of the heart are a risk group for particulate matter effects.
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spelling pubmed-25569242008-10-01 Are there sensitive subgroups for the effects of airborne particles? Zanobetti, A Schwartz, J Gold, D Environ Health Perspect Research Article Recent studies have shown that particulate air pollution is a risk factor for hospitalization for heart and lung disease; however, little is known about what subpopulations are most sensitive to this pollutant. We analyzed Medicare hospital admissions for heart disease, chronic obstructive pulmonary disorders (COPD) and pneumonia in Chicago, Cook County, Illinois, between 1985 and 1994. We examined whether previous admissions or secondary diagnoses for selected conditions predisposed persons to having a greater risk from air pollution. We also considered effect modification by age, sex, and race. We found that the air-pollution-associated increase in hospital admissions for cardiovascular diseases was almost doubled in subjects with concurrent respiratory infections. The risk was also increased by a previous admission for conduction disorders. For COPD and pneumonia admissions, diagnosis of conduction disorders or dysrhythmias increased the risk of particulate matter < 10 microm in aerodynamic diameter (PM(10))-associated admissions. Persons with asthma had twice the risk of a PM(10)-associated pneumonia admission and persons with heart failure had twice the risk of PM(10)-induced COPD admissions. The PM(10) effect did not vary by sex, age, and race. These results suggest that patients with acute respiratory infections or defects in the electrical control of the heart are a risk group for particulate matter effects. 2000-09 /pmc/articles/PMC2556924/ /pubmed/11017888 Text en
spellingShingle Research Article
Zanobetti, A
Schwartz, J
Gold, D
Are there sensitive subgroups for the effects of airborne particles?
title Are there sensitive subgroups for the effects of airborne particles?
title_full Are there sensitive subgroups for the effects of airborne particles?
title_fullStr Are there sensitive subgroups for the effects of airborne particles?
title_full_unstemmed Are there sensitive subgroups for the effects of airborne particles?
title_short Are there sensitive subgroups for the effects of airborne particles?
title_sort are there sensitive subgroups for the effects of airborne particles?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556924/
https://www.ncbi.nlm.nih.gov/pubmed/11017888
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