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Go with the flow: an updated tool for detecting molecules.

In the early 1970, researchers at Los Alamos National Laboratories developed the flow cytometer, a device that allows for the identification of unknown cells. In a flow cytometer, a single-cell suspension is passed in a continuous flow through a laser beam, with each cell scattering the light in a c...

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Detalles Bibliográficos
Autor principal: Frazer, L
Formato: Texto
Lenguaje:English
Publicado: 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556940/
https://www.ncbi.nlm.nih.gov/pubmed/11017903
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author Frazer, L
author_facet Frazer, L
author_sort Frazer, L
collection PubMed
description In the early 1970, researchers at Los Alamos National Laboratories developed the flow cytometer, a device that allows for the identification of unknown cells. In a flow cytometer, a single-cell suspension is passed in a continuous flow through a laser beam, with each cell scattering the light in a characteristic manner. A few years ago, researchers at Los Alamos began another project, refining the capabilities of the flow cytometer so that it could analyze not a single cell but a single molecule, allowing scientists to study bacteria at the molecular level, differentiating between individual strains more quickly and with greater accuracy than before. The new flow cytometer shows great promise in a variety of fields where single-molecule study would be valuable, such as genomics and disease transmission.
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spelling pubmed-25569402008-10-01 Go with the flow: an updated tool for detecting molecules. Frazer, L Environ Health Perspect Research Article In the early 1970, researchers at Los Alamos National Laboratories developed the flow cytometer, a device that allows for the identification of unknown cells. In a flow cytometer, a single-cell suspension is passed in a continuous flow through a laser beam, with each cell scattering the light in a characteristic manner. A few years ago, researchers at Los Alamos began another project, refining the capabilities of the flow cytometer so that it could analyze not a single cell but a single molecule, allowing scientists to study bacteria at the molecular level, differentiating between individual strains more quickly and with greater accuracy than before. The new flow cytometer shows great promise in a variety of fields where single-molecule study would be valuable, such as genomics and disease transmission. 2000-09 /pmc/articles/PMC2556940/ /pubmed/11017903 Text en
spellingShingle Research Article
Frazer, L
Go with the flow: an updated tool for detecting molecules.
title Go with the flow: an updated tool for detecting molecules.
title_full Go with the flow: an updated tool for detecting molecules.
title_fullStr Go with the flow: an updated tool for detecting molecules.
title_full_unstemmed Go with the flow: an updated tool for detecting molecules.
title_short Go with the flow: an updated tool for detecting molecules.
title_sort go with the flow: an updated tool for detecting molecules.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556940/
https://www.ncbi.nlm.nih.gov/pubmed/11017903
work_keys_str_mv AT frazerl gowiththeflowanupdatedtoolfordetectingmolecules