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Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites
The disinfectants TriGene, bleach, ethanol and liquid hand soap, and water and temperature were tested for their ability to kill bloodstream forms of Trypanosoma brucei, epimastigotes of Trypanosoma rangeli and promastigotes of Leishmania major. A 5-min exposure to 0.2% TriGene, 0.1% liquid hand soa...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556999/ https://www.ncbi.nlm.nih.gov/pubmed/18808700 http://dx.doi.org/10.1186/1756-3305-1-35 |
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author | Wang, Xia Jobe, Momodou Tyler, Kevin M Steverding, Dietmar |
author_facet | Wang, Xia Jobe, Momodou Tyler, Kevin M Steverding, Dietmar |
author_sort | Wang, Xia |
collection | PubMed |
description | The disinfectants TriGene, bleach, ethanol and liquid hand soap, and water and temperature were tested for their ability to kill bloodstream forms of Trypanosoma brucei, epimastigotes of Trypanosoma rangeli and promastigotes of Leishmania major. A 5-min exposure to 0.2% TriGene, 0.1% liquid hand soap and 0.05% bleach (0.05% NaOCl) killed all three trypanosomatids. Ethanol and water destroyed the parasites within 5 min at concentrations of 15–17.5% and 80–90%, respectively. All three organisms were also killed when treated for 5 min at 50°C. The results indicate that the disinfectants, water and temperature treatment (i.e. autoclaving) are suitable laboratory hygiene measures against trypanosomatid parasites. |
format | Text |
id | pubmed-2556999 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-25569992008-10-02 Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites Wang, Xia Jobe, Momodou Tyler, Kevin M Steverding, Dietmar Parasit Vectors Short Report The disinfectants TriGene, bleach, ethanol and liquid hand soap, and water and temperature were tested for their ability to kill bloodstream forms of Trypanosoma brucei, epimastigotes of Trypanosoma rangeli and promastigotes of Leishmania major. A 5-min exposure to 0.2% TriGene, 0.1% liquid hand soap and 0.05% bleach (0.05% NaOCl) killed all three trypanosomatids. Ethanol and water destroyed the parasites within 5 min at concentrations of 15–17.5% and 80–90%, respectively. All three organisms were also killed when treated for 5 min at 50°C. The results indicate that the disinfectants, water and temperature treatment (i.e. autoclaving) are suitable laboratory hygiene measures against trypanosomatid parasites. BioMed Central 2008-09-22 /pmc/articles/PMC2556999/ /pubmed/18808700 http://dx.doi.org/10.1186/1756-3305-1-35 Text en Copyright © 2008 Wang et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Report Wang, Xia Jobe, Momodou Tyler, Kevin M Steverding, Dietmar Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites |
title | Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites |
title_full | Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites |
title_fullStr | Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites |
title_full_unstemmed | Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites |
title_short | Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites |
title_sort | efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites |
topic | Short Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556999/ https://www.ncbi.nlm.nih.gov/pubmed/18808700 http://dx.doi.org/10.1186/1756-3305-1-35 |
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