A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma

BACKGROUND: The primary objective of this study was to determine the maximum tolerated dose (MTD) of escalating doses of radiotherapy (RT) concomitantly with a fixed dose of gemcitabine (300 mg/m(2)/week) within the same overall treatment time. METHODS: Thirteen patients were included. Gemcitabine 3...

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Detalles Bibliográficos
Autores principales: Budiharto, Tom, Haustermans, Karin, Van Cutsem, Eric, Van Steenbergen, Werner, Topal, Baki, Aerts, Raymond, Ectors, Nadine, Bielen, Didier, Vanbeckevoort, Dirk, Goethals, Laurence, Verslype, Chris
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557003/
https://www.ncbi.nlm.nih.gov/pubmed/18808686
http://dx.doi.org/10.1186/1748-717X-3-30

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