Knockdown of MBP-1 in Human Foreskin Fibroblasts Induces p53-p21 Dependent Senescence

MBP-1 acts as a general transcriptional repressor. Overexpression of MBP-1 induces cell death in a number of cancer cells and regresses tumor growth. However, the function of endogenous MBP-1 in normal cell growth regulation remains unknown. To unravel the role of endogenous MBP-1, we knocked down M...

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Detalles Bibliográficos
Autores principales: Ghosh, Asish K., Kanda, Tatsuo, Steele, Robert, Ray, Ratna B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557062/
https://www.ncbi.nlm.nih.gov/pubmed/18852884
http://dx.doi.org/10.1371/journal.pone.0003384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557062/
https://www.ncbi.nlm.nih.gov/pubmed/18852884
http://dx.doi.org/10.1371/journal.pone.0003384

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