Functional Deficits in nNOSμ-Deficient Skeletal Muscle: Myopathy in nNOS Knockout Mice

Skeletal muscle nNOSμ (neuronal nitric oxide synthase mu) localizes to the sarcolemma through interaction with the dystrophin-associated glycoprotein (DAG) complex, where it synthesizes nitric oxide (NO). Disruption of the DAG complex occurs in dystrophinopathies and sarcoglycanopathies, two genetic...

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Detalles Bibliográficos
Autores principales: Percival, Justin M., Anderson, Kendra N. E., Gregorevic, Paul, Chamberlain, Jeffrey S., Froehner, Stanley C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559862/
https://www.ncbi.nlm.nih.gov/pubmed/18852886
http://dx.doi.org/10.1371/journal.pone.0003387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559862/
https://www.ncbi.nlm.nih.gov/pubmed/18852886
http://dx.doi.org/10.1371/journal.pone.0003387

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