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ILOOP – a web application for two-channel microarray interwoven loop design
Microarray technology is widely applied to address complex scientific questions. However, there remain fundamental issues on how to design experiments to ensure that the resulting data enables robust statistical analysis. Interwoven loop design has several advantages over other designs. However it s...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559875/ https://www.ncbi.nlm.nih.gov/pubmed/18831776 http://dx.doi.org/10.1186/1471-2164-9-S2-S11 |
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author | Pirooznia, Mehdi Gong, Ping Yang, Jack Y Yang, Mary Qu Perkins, Edward J Deng, Youping |
author_facet | Pirooznia, Mehdi Gong, Ping Yang, Jack Y Yang, Mary Qu Perkins, Edward J Deng, Youping |
author_sort | Pirooznia, Mehdi |
collection | PubMed |
description | Microarray technology is widely applied to address complex scientific questions. However, there remain fundamental issues on how to design experiments to ensure that the resulting data enables robust statistical analysis. Interwoven loop design has several advantages over other designs. However it suffers in the complexity of design. We have implemented an online web application which allows users to find optimal loop designs for two-color microarray experiments. Given a number of conditions (such as treatments or time points) and replicates, the application will find the best possible design of the experiment and output experimental parameters. It is freely available from . |
format | Text |
id | pubmed-2559875 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-25598752008-10-04 ILOOP – a web application for two-channel microarray interwoven loop design Pirooznia, Mehdi Gong, Ping Yang, Jack Y Yang, Mary Qu Perkins, Edward J Deng, Youping BMC Genomics Research Microarray technology is widely applied to address complex scientific questions. However, there remain fundamental issues on how to design experiments to ensure that the resulting data enables robust statistical analysis. Interwoven loop design has several advantages over other designs. However it suffers in the complexity of design. We have implemented an online web application which allows users to find optimal loop designs for two-color microarray experiments. Given a number of conditions (such as treatments or time points) and replicates, the application will find the best possible design of the experiment and output experimental parameters. It is freely available from . BioMed Central 2008-09-16 /pmc/articles/PMC2559875/ /pubmed/18831776 http://dx.doi.org/10.1186/1471-2164-9-S2-S11 Text en Copyright © 2008 Pirooznia et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Pirooznia, Mehdi Gong, Ping Yang, Jack Y Yang, Mary Qu Perkins, Edward J Deng, Youping ILOOP – a web application for two-channel microarray interwoven loop design |
title | ILOOP – a web application for two-channel microarray interwoven loop design |
title_full | ILOOP – a web application for two-channel microarray interwoven loop design |
title_fullStr | ILOOP – a web application for two-channel microarray interwoven loop design |
title_full_unstemmed | ILOOP – a web application for two-channel microarray interwoven loop design |
title_short | ILOOP – a web application for two-channel microarray interwoven loop design |
title_sort | iloop – a web application for two-channel microarray interwoven loop design |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559875/ https://www.ncbi.nlm.nih.gov/pubmed/18831776 http://dx.doi.org/10.1186/1471-2164-9-S2-S11 |
work_keys_str_mv | AT piroozniamehdi iloopawebapplicationfortwochannelmicroarrayinterwovenloopdesign AT gongping iloopawebapplicationfortwochannelmicroarrayinterwovenloopdesign AT yangjacky iloopawebapplicationfortwochannelmicroarrayinterwovenloopdesign AT yangmaryqu iloopawebapplicationfortwochannelmicroarrayinterwovenloopdesign AT perkinsedwardj iloopawebapplicationfortwochannelmicroarrayinterwovenloopdesign AT dengyouping iloopawebapplicationfortwochannelmicroarrayinterwovenloopdesign |