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The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury

BACKGROUND: Altered Cl(- )homeostasis and GABAergic function are associated with nociceptive input hypersensitivity. This study investigated the role of two major intracellular Cl(- )regulatory proteins, Na(+)-K(+)-Cl(- )cotransporter 1 (NKCC1) and K(+)-Cl(- )cotransporter 2 (KCC2), in neuropathic p...

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Detalles Bibliográficos
Autores principales: Cramer, Samuel W, Baggott, Christopher, Cain, John, Tilghman, Jessica, Allcock, Bradley, Miranpuri, Gurwattan, Rajpal, Sharad, Sun, Dandan, Resnick, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561007/
https://www.ncbi.nlm.nih.gov/pubmed/18799000
http://dx.doi.org/10.1186/1744-8069-4-36