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G-CSFR Ubiquitination Critically Regulates Myeloid Cell Survival and Proliferation

The granulocyte colony-stimulating factor receptor (G-CSFR) is a critical regulator of granulopoiesis. Mutations in the G-CSFR in patients with severe congenital neutropenia (SCN) transforming to acute myelogenous leukemia (AML) have been shown to induce hypersensitivity and enhanced growth response...

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Detalles Bibliográficos
Autores principales:	Ai, Jing, Druhan, Lawrence J., Loveland, Megan J., Avalos, Belinda R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561048/ https://www.ncbi.nlm.nih.gov/pubmed/18923646 http://dx.doi.org/10.1371/journal.pone.0003422

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