A comparison of MSA tools

Multiple sequence alignment (MSA) is essential in phylogenetic, evolutionary and functional analysis. Several MSA tools are available in the literature. Here, we use several MSA tools such as ClustalX, Align-m, T-Coffee, SAGA, ProbCons, MAFFT, MUSCLE and DIALIGN to illustrate comparative phylogeneti...

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Detalles Bibliográficos
Autores principales: Essoussi, Nadia, Boujenfa, Khaddouja, Limam, Mohamed
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2008
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561165/
https://www.ncbi.nlm.nih.gov/pubmed/18841241
Descripción
Sumario:Multiple sequence alignment (MSA) is essential in phylogenetic, evolutionary and functional analysis. Several MSA tools are available in the literature. Here, we use several MSA tools such as ClustalX, Align-m, T-Coffee, SAGA, ProbCons, MAFFT, MUSCLE and DIALIGN to illustrate comparative phylogenetic trees analysis for two datasets. Results show that there is no single MSA tool that consistently outperforms the rest in producing reliable phylogenetic trees.

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