A comparison of MSA tools

Multiple sequence alignment (MSA) is essential in phylogenetic, evolutionary and functional analysis. Several MSA tools are available in the literature. Here, we use several MSA tools such as ClustalX, Align-m, T-Coffee, SAGA, ProbCons, MAFFT, MUSCLE and DIALIGN to illustrate comparative phylogeneti...

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Detalles Bibliográficos
Autores principales: Essoussi, Nadia, Boujenfa, Khaddouja, Limam, Mohamed
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2008
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561165/
https://www.ncbi.nlm.nih.gov/pubmed/18841241
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author Essoussi, Nadia
Boujenfa, Khaddouja
Limam, Mohamed
author_facet Essoussi, Nadia
Boujenfa, Khaddouja
Limam, Mohamed
author_sort Essoussi, Nadia
collection PubMed
description Multiple sequence alignment (MSA) is essential in phylogenetic, evolutionary and functional analysis. Several MSA tools are available in the literature. Here, we use several MSA tools such as ClustalX, Align-m, T-Coffee, SAGA, ProbCons, MAFFT, MUSCLE and DIALIGN to illustrate comparative phylogenetic trees analysis for two datasets. Results show that there is no single MSA tool that consistently outperforms the rest in producing reliable phylogenetic trees.
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spelling pubmed-25611652008-10-07 A comparison of MSA tools Essoussi, Nadia Boujenfa, Khaddouja Limam, Mohamed Bioinformation Hypothesis Multiple sequence alignment (MSA) is essential in phylogenetic, evolutionary and functional analysis. Several MSA tools are available in the literature. Here, we use several MSA tools such as ClustalX, Align-m, T-Coffee, SAGA, ProbCons, MAFFT, MUSCLE and DIALIGN to illustrate comparative phylogenetic trees analysis for two datasets. Results show that there is no single MSA tool that consistently outperforms the rest in producing reliable phylogenetic trees. Biomedical Informatics Publishing Group 2008-07-31 /pmc/articles/PMC2561165/ /pubmed/18841241 Text en © 2008 Biomedical Informatics Publishing Group This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Hypothesis
Essoussi, Nadia
Boujenfa, Khaddouja
Limam, Mohamed
A comparison of MSA tools
title A comparison of MSA tools
title_full A comparison of MSA tools
title_fullStr A comparison of MSA tools
title_full_unstemmed A comparison of MSA tools
title_short A comparison of MSA tools
title_sort comparison of msa tools
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561165/
https://www.ncbi.nlm.nih.gov/pubmed/18841241
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