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Control of Parasitophorous Vacuole Expansion by LYST/Beige Restricts the Intracellular Growth of Leishmania amazonensis
The intracellular protozoan Leishmania replicates in parasitophorous vacuoles (PV) that share many features with late endosomes/lysosomes. L. amazonensis PVs expand markedly during infections, but the impact of PV size on parasite intracellular survival is still unknown. Here we show that host cells...
Autores principales: | Wilson, Jude, Huynh, Chau, Kennedy, Kathleen A., Ward, Diane M., Kaplan, Jerry, Aderem, Alan, Andrews, Norma W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562527/ https://www.ncbi.nlm.nih.gov/pubmed/18927622 http://dx.doi.org/10.1371/journal.ppat.1000179 |
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