High throughput drug profiling

High throughput screening has significantly contributed to advances in drug discovery. The great increase in the number of samples screened has been accompanied by increases in costs and in the data required for the investigated compounds. High throughput profiling addresses the issues of compound s...

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Detalles Bibliográficos
Autores principales: Entzeroth, Michael, Chapelain, Béatrice, Guilbert, Jacques, Hamon, Valérie
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562836/
https://www.ncbi.nlm.nih.gov/pubmed/18924690
http://dx.doi.org/10.1155/S1463924600000304
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author Entzeroth, Michael
Chapelain, Béatrice
Guilbert, Jacques
Hamon, Valérie
author_facet Entzeroth, Michael
Chapelain, Béatrice
Guilbert, Jacques
Hamon, Valérie
author_sort Entzeroth, Michael
collection PubMed
description High throughput screening has significantly contributed to advances in drug discovery. The great increase in the number of samples screened has been accompanied by increases in costs and in the data required for the investigated compounds. High throughput profiling addresses the issues of compound selectivity and specificity. It combines conventional screening with data mining technologies to give a full set of data, enabling development candidates to be more fully compared.
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spelling pubmed-25628362008-10-16 High throughput drug profiling Entzeroth, Michael Chapelain, Béatrice Guilbert, Jacques Hamon, Valérie J Autom Methods Manag Chem Research Article High throughput screening has significantly contributed to advances in drug discovery. The great increase in the number of samples screened has been accompanied by increases in costs and in the data required for the investigated compounds. High throughput profiling addresses the issues of compound selectivity and specificity. It combines conventional screening with data mining technologies to give a full set of data, enabling development candidates to be more fully compared. Hindawi Publishing Corporation 2000 /pmc/articles/PMC2562836/ /pubmed/18924690 http://dx.doi.org/10.1155/S1463924600000304 Text en Copyright © 2000 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Entzeroth, Michael
Chapelain, Béatrice
Guilbert, Jacques
Hamon, Valérie
High throughput drug profiling
title High throughput drug profiling
title_full High throughput drug profiling
title_fullStr High throughput drug profiling
title_full_unstemmed High throughput drug profiling
title_short High throughput drug profiling
title_sort high throughput drug profiling
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562836/
https://www.ncbi.nlm.nih.gov/pubmed/18924690
http://dx.doi.org/10.1155/S1463924600000304
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AT chapelainbeatrice highthroughputdrugprofiling
AT guilbertjacques highthroughputdrugprofiling
AT hamonvalerie highthroughputdrugprofiling

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