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PP2A-Mediated Dephosphorylation of p107 Plays a Critical Role in Chondrocyte Cell Cycle Arrest by FGF

FGF signaling inhibits chondrocyte proliferation, a cell type-specific response that is the basis for several genetic skeletal disorders caused by activating FGFR mutations. This phenomenon requires the function of the p107 and p130 members of the Rb protein family, and p107 dephosphorylation is one...

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Detalles Bibliográficos
Autores principales:	Kolupaeva, Victoria, Laplantine, Emmanuel, Basilico, Claudio
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562983/ https://www.ncbi.nlm.nih.gov/pubmed/18927618 http://dx.doi.org/10.1371/journal.pone.0003447

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